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Our research is at the interface of cell biology, biophysics, and advanced imaging technology.  We develop and apply superresolution microscopy and advanced imaging techniques to understand how cells built complex nanoscale machines from basic biomolecular building blocks to perform vital biological functions.  

We focus on cell adhesions and cytoskeletal systems important for mechanobiology: Focal Adhesions, Adherens Junctions, Actin Cortex, and Microtubules.

Superresolution Microscopy

Our Microscopes

Integrin-mediated Cell-Matrix Interactions


Cadherin-mediated Cell-Cell Interactions


Home: News


Congratulations to our former postdoc Prof. Cristina Bertocchi for a publication in Nature Communications

(July 2024)

Congratulations to Kashish and our collaborators for a publication in Advanced Materials

(March 2024)


Farewell to Kashish and Xueying

(December 2023)

Congratulations to Xueying for a successful Ph.D. thesis defense 

(November 2023)

Congratulations to Kin Sun for a successful Ph.D. thesis defense 

(November 2023)

Congratulations to our collaborator Tsang Mankei for a publicaion in Optica

(September 2023)

Farewell to Liu Shiying and Arulchelval

(September 2023)

Warm welcome to Kyna Lim

(August 2023)

Home: CV


November 25_2010 Nature Cover Web.jpg


  • Nicole Morales, Jingzhun Liu, Manuel J. Ramirez, Patricio Canales-Salgado, Juan José Alegría, Xuyao Liu, Hui Ting Ong, Nelson Barrera, Angélica Fierro, Yusuke Toyama, Benjamin T. Goult, Yilin Wang, Yue Meng, Ryosuke Nishimura, Kedsarin Fong-Ngern, Christine Siok Lan Low, Pakorn Kanchanawong, Jie Yan, Andrea Ravasio, and Cristina Bertocchi “Alternative molecular mechanics of force transmission at adherens junction via β-catenin-vinculin interaction” Nature Communications 15, 5608 (2024) (2024)

  • Julien Aureille, Srinivas S Prabhu, Samuel F Barnett, Aaron J Farrugia, Isabelle Arnal, Laurence Lafanechère, Boon Chuan Low, Pakorn Kanchanawong, Alex Mogilner, Alexander D Bershadsky, “Focal adhesions are controlled by microtubules through local contractility regulation”. EMBO Journal (2024)

  • Kashish Jain, Ashish Pandey, Hao Wang, Taerin Chung, Arash Nemati, Pakorn Kanchanawong, Michael P. Sheetz, Haogang Cai, Rishita Changede “TiO2 Nano-Biopatterning Reveals Optimal Ligand Presentation for Cell-Matrix Adhesion Formation” Advanced Materials

  • Xiao-Jie Tan, Luo Qi, Lianwei Chen, Aaron J. Danner, Pakorn Kanchanawong, Mankei Tsang “Towards practical quantum-inspired superresolution for multiple incoherent sources” Optica 10 (9), 1189-1194 (2023)

  • Zengxin Huang, Pakorn Kanchanawong, “Ultra High-Speed Single-Molecule Imaging” Journal of Cell Biology 222, no. 8 (2023)

  • Y. H. Tee, W. J. Goh, X. Yong, H. T. Ong, J. Hu, I. Y. Y. Tay, S. Shi, S. Jalal, S. F. H. Barnett, P. Kanchanawong, W. Huang, J. Yan, Y.A.B. Lim, V. Thiagarajan, A. Mogilner, A. D. Bershadsky. “Actin polymerization and crosslinking drive individual and collective cell left-right asymmetry” Nature Communications  4, 776 (2023). doi: 10.1038/s41467-023-35918-1

  • Jiachuan Bai, Wei Ouyang, Manish Singh, Christophe Leterrier, Paul Barthelemy, Samuel F.H. Barnett, Teresa Klein, Markus Sauer, Pakorn Kanchanawong, Nicolas Bourg, Mickael Cohen, Benoît Lelandais, Christophe Zimmer. “ShareLoc – an open platform for sharing localization microscopy data” Nature Methods, 2022,

  • Pakorn Kanchanawong*, David Calderwood*, “Organisation, dynamics and mechanoregulation of integrin-mediated cell–ECM adhesions” Nature Reviews Molecular and Cellular Biology, 2022, doi:10.1038/s41580-022-00531-5

  • Self-supervised classification of subcellular morphometric phenotypes reveals extracellular matrix-specific morphological responses, Kin Sun Wong, Xueying Zhong, Christine Siok Lan Low, and Pakorn Kanchanawong Scientific Reports, 2022, doi: 10.1038/s41598-022-19472-2

  • Darren Chen Pei Wong, Jingwei Xiao, Ti Weng Chew, Meng Pan, Chang Jie Mick Lee, Jing Wen Ang, Ivan Yow, T. Thivakar, Matthew Ackers-Johnson, Nicole Jia Wen Lee, Roger Sik-Yin Foo, Pakorn Kanchanawong*, Boon Chuan Low*. “BNIP-2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation” Advanced Science, 2022, 2202834. doi:10.1002/advs.202202834

  • Kashish Jain, Pakorn Kanchanawong, Michael P. Sheetz, Haogang Cai, Rishita Chengede. “Ligand functionalization of titanium nanopattern enables the analysis of cell–ligand interactions by super-resolution microscopy” Nature Protocols 2022, 1-33. doi: 10.1038/s41596-022-00717-3

  • Shiying Liu, Pakorn Kanchanawong, “Emerging Interplay of Cytoarchitecture, Cytomechanics, and Pluripotency Regulation” Journal of Cell Science (135, no. 12 (2022): jcs259379

  • Shiying Liu, Zhen Zhang, Pakorn Kanchanawong. “Meshworks Analyzer: Quantitative analysis software for super-resolved actin cortex architecture” Software Impacts

  • M. Joy-Immediato, R. M. Ramirez, M. Cerda, Y. Toyama, A. Ravasio, P. Kanchanawong*, C. Bertocchi*. “ER structural organization affects mechanotransduction at cadherin-based adhesions by modulating PTP1B activity.” Frontiers in Cell and Developmental Biology doi: 10.3389/fcell.2021.669086 *: co-corresponding authors

  • Azita Gorji, Pearlyn Jia Ying Toh, Hui Ting Ong, Yi-Chin Toh, Yusuke Toyama, Pakorn Kanchanawong. “The enhancement of endothelialization by topographical features is mediated by PTP1B-dependent endothelial adherens junctions remodeling.” ACS Biomaterials Science and Engineering doi:10.1021/acsbiomaterials.1c00251


  • Miao Yu, Shimin Le, Samuel Barnett, Zhenhuan Guo, Xueying Zhong, Pakorn Kanchanawong* and Jie Yan* “Implementing Optogenetic Modulation in Mechanotransduction.”  Physical Review X 10 (2), 021001 *: corresponding authors

  • D. Thumkeo, Y. Katsura, P. Beemiller, Y. Nishimura, P. Kanchanawong, T. Ishizaki, S. Kitajima, C. Takahashi, T. Hirata,  N. Watanabe, M. F. Krummel, S. Narumiya. “mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse” Science Advances. 6(1):eeay2432, 2020 doi: 10.1126/sciadv.aay2432

  • Yinan Wang#, Samuel Barnett#, Shimin Le, Zhenhuan Guo, Xueying Zhong, Pakorn Kanchanawong*, Jie Yan*. “Label-free single-molecule quantification of rapamycin-induced FKBP-FRB dimerization for Direct Control of Cellular Mechanotransduction” Nano Letters 19(10) 7514-7525  ​#:co-first authors, *: co-corresponding authors doi:10.1021/acs.nanolett.9b03364

  • Shumin Xia, Bena Lim, Yilin Wang, Zhen Zhang, Shan Zhang, Chwee Teck Lim, Evelyn K. F. Yim, Pakorn Kanchanawong, “Nanoscale Architecture of the Cortical Actin Cytoskeletons in Embryonic Stem Cells” Cell Reports 28(5), P1251-1267.E7 (2019) doi:10.1016/j.celrep.2019.06.089

  • Nisha Bte Mohd Rafiq#, Yukako Nishimura#, Sergey V Plotnikov, Visalatchi Thiagarajan, Zhen Zhang, Shidong Shi, Meenubharathi Natarajan, Virgile Viasnoff, Pakorn Kanchanawong*, Gareth Jones*, and Alexander D. Bershadsky* "A mechano-signalling network linking microtubules, myosin-IIA filaments and integrin-based adhesions" Nature Materials 18, 638-649 (2019). doi:10.1038/s41563-019-0371-y

       #:co-first authors, *: co-corresponding authors

  • Yun-Chi Tsai, Wei-Chun Tang, Christine Siok Lan Low, Yen-Ting Liu, Jyun-Sian Wu, Po-Yi Lee, Pakorn Kanchanawong, Liang Gao, and Bi-Chang Chen “Rapid High Resolution 3D Imaging of Expanded Biological Specimens with Lattice Light Sheet Microscopy”  Methods doi: 10.1016/ j.ymeth.2019. 04.006

  • Shumin Xia, Evelyn K. F. Yim, Pakorn Kanchanawong, “Molecular Organization of Integrin-based Adhesion Complexes in mouse Embryonic Stem Cells”, ACS Biomaterials Sciences and Engineering 5(8), 3828-3842 (2019). doi:10.1021/acsbiomaterials.8b01124

  • Samuel F. H. Barnett, Pakorn Kanchanawong. “Visualizing the backbone of focal adhesions” Emerging Topics in Life Sciences 2 (5), 677-680 (2018)

  • Satoko Sakamoto, Dean Thumkeo, Hiroshi Ohta, Zhen Zhang, Pakorn Kanchanawong, Takayoshi Fu, Sadanori Watanabe, Yoshitaka Fujiwara, Masahito Ikawa, Naoki Watanabe, Mitinori Saitou and Shuh Narumiya  “mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility” PLOS Biology 2018; 9: e2004874 10.1371/journal.pbio.2004874

  • Ravikrishna Ramanujam, Ziyin Han, Zhen Zhang, Pakorn Kanchanawong, and Fumio Motegi. “Establishment of the PAR-1 cortical gradient by the aPKC-PRBH circuit.” Nature Chemical Biology 2018; 14:917-927

  • Chwee Tat Koe, Ye Sing Tan, Max Lönnfors, Seong Kwon Hur, Christine Siok Lan Low, Yingjie Zhang, Pakorn Kanchanawong, Vytas A. Bankaitis, Hongyan Wang. “Vibrator and PI4KIIIa Govern Neuroblast Polarity by Anchoring Non-muscle Myosin II” eLife 2018; 7:e33555 doi: 10.7554/eLife.33555

  • Zhen Zhang, Yen Wei Lim, Peng Zhao, Pakorn Kanchanawong*, Fumio Motegi*. “ImaEdge: A quantitative image analysis platform for cortical protein dynamics during cell polarization.” Journal of Cell Science 2017: 130(24), 4200-4212 doi: 10.1242/jcs.206870  * co-corresponding authors

  • Rupprecht JF, Martinez-Marrades A, Changede R, Zhang Z, Kanchanawong P, Tessier G. "Trade-offs between spatial and temporal resolutions in stochastic super-resolution microscopy techniques" Optics Express 25(19), 23146-23163 (2017). doi:10.1364/OE.25.023146

  • Shumin Xia, Pakorn Kanchanawong. "Nanoscale Mechanobiology of Cell Adhesions" Seminars in Cell and Developmental Biology (2017) doi:10.1016/j.semcdb.2017.07.029

  • Zhen Zhang, Shumin Xia, Pakorn Kanchanawong. “An Integrated Enhancement and Reconstruction Strategy for the Quantitative Extraction of Actin Stress Fibers from Fluorescence Micrographs” BMC Bioinformatics (2017) 18:268. doi: 10.1186/s12859-017-1684-y.

  • Kapish Gupta, Qiushi Li, Jun Jun Fan, Eliza Li Shan Fong, Ziwei Song, Shupei Mo, Haoyu Tang, Inn Chuan Ng, Chan Way Ng, Pornteera Pawijit, Shuangmu Zhuo, Chen-Yuan Dong, Boon Chuan Low, Aileen Wee, Yock Young Dan, Pakorn Kanchanawong, Peter So, Virgile Viasnoff, Hanry Yu. "Actomyosin Contractility Drives Bile Regurgitation as an Early Response During Obstructive Cholestasis" Journal of Hepatology, 66(6), 1231-1240, 2017.  doi:10.1016/j.jhep.2017.01.026

  • Cristina Bertocchi, Yilin Wang, Andrea Ravasio, Yusuke Hara, Yao Wu, Talgat Sailov, Michelle A. Baird, Michael W. Davidson, Ronen Zaidel-Bar, Yusuke Toyama, Benoit Ladoux, Rene-Marc Mege, and Pakorn Kanchanawong. “Nanoscale architecture of cadherin-based cell adhesions” Nature Cell Biology 19 (1), 28-37, 2017. doi:10.1038/ncb3456              *  News and Views in Nature Cell Biology

  • Yeo ELL, Joshua U, Cheah J, Neo DJH, Goh WI, Kanchanawong P, Soo KC, Thong PSP, Kah JCY: "Exploiting the protein corona around gold nanorods for low-dose combined photothermal and photodynamic therapy." Journal of Materials Chemistry B, 5 (2), 254-268, 2017. doi: 10.1039/C6TB02743A 

  • Z Zhang, Y Nishimura, P Kanchanawong "Extracting Microtubule Networks from Superresolution Single-Molecule Localization Microscopy Data" Molecular Biology of the Cell, 28 (2), 333-345, 2017. doi:10.1091/mbc.E16-06-0421

  • ​Wang, Y., Kanchanawong, P. "Three-dimensional Super Resolution Microscopy of F-actin Filaments by Interferometric PhotoActivated Localization Microscopy (iPALM)." J. Vis. Exp. (118), e54774, doi:10.3791/54774 (2016). doi: 10.3791/54774

  • J. Liu, Y. Wang, W. I. Goh, H. Goh, M. A. Baird, S. Ruehland, S. Teo, N. Bate, D. R.   Critchley, M. W. Davidson, P. Kanchanawong, “Talin determines the nanoscale architecture of focal adhesions” PNAS, 112 (35), E4864-E4873. doi: 10.1073/pnas.1512025112

  • Y. Wu, P. Kanchanawong, R. Zaidel-Bar, “Actin-Delimited Adhesion-Independent Clustering of E-Cadherin Forms the Nanoscale Building Blocks of Adherens Junctions”   Developmental Cell. (2015)  32 (2), 139-154. doi: 10.1016/j.devcel.2014.12.003

  • G. Shtengel, Y. Wang, Z. Zhang, W. I. Goh, H. F. Hess, P. Kanchanawong. “Imaging cellular ultra-structure by PALM, iPALM, and correlative iPALM-EM.” Methods In Cell Biology, Elsevier (Eds. T. Wittman & J. Waters), (2014). doi: 10.1016/B978-0-12-420138-5.00015-X

  • C. Bertocchi, W. I. Goh, Z. Zhang, P. Kanchanawong. “Nanoscale Imaging by Superresolution Fluorescence Microscopy and Its Emerging Applications in Biomedical Research.” Critical Reviews in Biomedical Engineering, 41.4-5 (2013). doi: 10.1615/CritRevBiomedEng.2014010448 

  • A. Nomachi, M. Yoshinaga, J. Liu, P. Kanchanawong, D. Thumkeo, T Watanabe, S. Narumiya, T. Hirata. “Moesin Controls Clathrin-Mediated S1PR1 Internalization in T Cells”. Plos ONE. 8(12): e82590, 2013. doi:10.1371/journal.pone.0082590

  • P. Kanchanawong, C. M. Waterman. “Localization-based Super-resolution Imaging of Cellular Structures”, Adhesion Protein Protocols, Methods in Molecular Biology, Humana Press, A. Coutts (ed.), 1046:59-84, 2013. doi:10.1007/978-1-62703-538-5_4

  • G. Shtengel, J. Galbraith, C. Galbraith, P. Kanchanawong, C. Waterman, H. Hess. “Multicolor Interferometric Photo-Activation Localization Microscopy with Extended Axial Range”, Microscopy and Microanalysis, 17(S2): 6-7, 2011. doi:10.1017/S1431927611000900

  • P. Kanchanawong, C. M. Waterman. “Advances in light-based imaging of three-dimensional cellular ultrastructure”, Current Opinion in Cell Biology, 24:1-9, 2011 doi:10.1016/

  • R.S. Fischer, Y. Wu, P. Kanchanawong, H. Shroff, C. M. Waterman. “Microscopy in 3D: a biologist’s toolbox”, Trends in Cell Biology, 21(12): 682-691, 2011. doi:10.1016/j.tcb.2011.09.008

NIH (2007-11)

  • P. Kanchanawong, G. Shtengel, A. Pasapera-Limon, E. Ramko, M.W. Davidson, H.F. Hess, C. M. Waterman. “Nanoscale Architecutre of Integrin-based Adhesions”, Nature, 468(7323): 580-4, 2010.  doi:10.1038/nature09621

  • W.D. Shin, R.S. Fischer, P. Kanchanawong, Y. Kim, J. Lim, K.A. Meyers, Y. Nishimura, S.V. Plotnikov, I. Thievessen, D. Yarar, B. Sabass, C.M. Waterman, A Versatile, Multicolor Total Internal Reflection Fluorescence and Spinning Disk Confocal Microscope System for High-Resolution Live Cell Imaging, in: R.D. Goldman, J.R. Swedlow, D.L. Spector (Eds.), Live Cell Imaging: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 2010.

  •  G. Shtengel, J. A. Galbraith, C. G. Galbraith, J. Lippincott-Schwartz, J. M. Gillette, S. Manley, R. Sougrat, C. M. Waterman, P. Kanchanawong, M. W. Davidson, R. D. Fetter and H. F. Hess.  “Interferometric fluorescent super-resolution microscopy resolves 3D cellular ultrastructure”, PNAS, 106 (9), 3125-3130, 2009. doi: 10.1073/pnas.0813131106

Stanford (2001-07)

  •   L. N. Silverman, P. Kanchanawong, T. P. Treynor, S. G. Boxer. “Stark spectroscopy of mixed valence systems”, Phil. Trans. R. Soc. A, 366, 33-45, 2008. doi: 10.1098/rsta.2007.2137

  •  X. Shu, K. Kallio, X. Shi, P. Abbyad, P. Kanchanawong, W. Childs, S. G. Boxer, and S. J. Remington. “Ultrafast Excited-State Dynamics in the Green Fluorescent Protein Variant S65T/H148D. 1. Mutagenesis and Structural Studies”, Biochemistry, 46 (43), 12005 -12013, 2007. doi: 10.1021/bi7009037        

  •    X. Shi, Paul Abbyad, X. Shu, K. Kallio, P. Kanchanawong, W. Childs, S. J. Remington, and S. G. Boxer. “Ultrafast Excited-State Dynamics in the Green Fluorescent Protein Variant S65T/H148D. 2. Unusual Photophysical Properties”, Biochemistry, 46 (43), 12014 -12025, 2007.  doi: 10.1021/bi700904a        

  •   P. Kanchanawong, M. G. Dahlbom, T. P. Treynor, J. R. Reimers, N.S. Hush and S. G. Boxer, “Charge delocalization in the special pair radical cation of mutant reaction centers of Rhodobacter sphaeroides from Stark spectra and non-adiabatic spectral simulations”, J. Phys. Chem. B. 110 (37), 18688-18702, 2006. doi: 10.1021/jp0623894

Cornell (1997-2001)

  •  G. Andre, P. Kanchanawong, R. Palma, H. Cho, X. Deng, D. Irwin, M. E. Himmel, D. B. Wilson and J. W. Brady, “Computational and experimental studies of the catalytic mechanism of Thermobifida fusca Cellulase Cel6A (E2)”, Protein Engineering. Vol. 16: 125-134, 2003. doi: 10.1093/proeng/gzg017

Home: TeamMember

Pakorn (Tony)


Principal Investigator, MBI

Associate Professor, Dept. of Biomedical Engineering, NUS

Ph.D. 2007

Stanford University  

A.B. (summa cum laude) 2001

Cornell University 


Wang Wei

Research Fellow

Ph. D. 2015

Huazhong University of Science and Technology

B. Sc. 2011

Huazhong University of Science and Technology



Wang Yilin

Research Fellow

Ph. D. 2009

City University of New York

M.Eng. 2002

B. Eng. 1999

South China University of Technology


Kedsarin Fong-ngern

Research Fellow

Ph. D. 2012

Mahidol University

B. Sc. 2005

Chiang Mai University



Ryosuke Nishimura

Research Fellow

Ph.D. 2022

Tokushima University

M.Sc. 2017

Tohoku University

B. Sc. 2015

Tohoku University


Kyna Lim

Research Assistant

B. Eng. 2023

National University of Singapore



Meng Yue

Graduate Student

M.Sc. 2020 Institute of Genetics and Developmental Biology, Chinese Academy of Sciences

B.Sc. 2016 Shandong Agricultural University


Xu Mengqing.JPG

Xu Mengqing

Graduate Student

M.Sc. 2020 Yale University

B.Sc. 2018 Emory University


Huang Zengxin

Graduate Student

M.Eng. 2021

B. Eng. 2018

Nankai University


Photograph-Zengxin Huang.jpg

Li Hangfeng

Graduate Student

M.Eng. 2022

University of Science and Technology of China

B.Eng. & B.Econ. 2019

Ningbo University



Co-supervised Graduate Student

Harini Rajendiran (with  Virgile Viasnoff)

Kuo Xuan (with Winston Zhao)

Undergraduates (& current positions)

Chong Shao Hong (FYP 2023)

Samuel Quek (FYP 2022)

Kyna Lim (FYP 2022)

Chai Jun Hao (FYP 2021)

Eldred Sng (FYP 2021, Duke-NUS)

Jonathan San (FYP 2021)

Ka Hui Yi (FYP 20201)

Cheryl Lee (FYP 2020, Illumina Inc.)

Kallista Wong (Independent Study 2020)

An Honglin (FYP, MSc NUS Mathematics)  

Samantha Chang Shi Min (Research Attachment/FYP 2018-2019, Research Assistant MBI)

Kevin Lim Zi Rong (FYP)

Arulchevan Vijayakumar (FYP2019, Research Assistant MBI)

Julian Siew Tze Kang (FYP)

Elena Poh Woon Li (FYP)

Sim Yi Herng (FYP, Micron Technology)

Wong Kin Sun (FYP, PhD student Biomedical Engineering)

Kwok Zi Jun (Research attachment)

Udpa Namitha Sujit (FYP) 

Ankshita Prasad (FYP, Research Fellow NUS) 

Akshaya Srinivisan (FYP, Research Fellow NUS)

Former Lab Members (& current positions)

Zhong Xueying, Ph.D. (Wuxi Biologics)

Kashish Jain, Ph.D. (Valerie Weaver group, University of California, San Francisco)

Wong Kin Sun, Ph.D. (Hendricks Corporation, Singapore)

Liu Shiying, Ph.D. (Nanyang Technological University)

Christine Low (National Heart Centre Singapore)

April Kyi Thwin (Moderna Inc. USA)

Chen Youchao (Graduate student, University of Warwick, UK)

Xia Shumin, Ph.D. (Wuxi Biologics, China)

Zhang Yuzi (Graduate student, HKUST, Hong Kong SAR)

Azita Gorji, Ph.D. (Postdoctoral Fellow, Institut Curie, Paris, France)

Cristina Bertocchi, Ph. D. (Assistant Professor, Pontificia Universidad Catolica de Chile, Santiago, Chile)

Yukako Nishimura, Ph.D. (Hokkaido University, Japan)

Zhang Zhen, Ph. D. (Tiktok Inc.)

Huang Shuangru, Ph. D. (SpesBio Ltd., Hangzhou, China)

Gary Guo Zhenhuan

Goh Wah Ing, Ph. D. (A*STAR Microscopy Platform)

Tian Xingyue (Chengdu, China)

Chaw Su Thwin (Research Associate, Nanyang Technological University)
Teo Shijia (Postdoctoral Fellow, Max Planck Institute, Tubingen, Germany)
Jaron Liu, Ph. D. (Mayo Clinic)

Goh Honzhen (Research Assistant, NUS)

Talgat Sailov (Zeiss Microscopy)

Svenja Ruehland (Ph.D. Student, Ludwig Maximillian University of Munich, Germany)

Ratul Chowdhury (Assistant Professor, Iowa State Univeristy, USA)

Eric Li, Ph. D. (Postdoctoral Fellow, University of Sydney, Australia)


Home: Contact


Position: Postdoctoral Fellow or Research Associate

We are looking for a Postdoctoral Fellow (Research Fellow/Senior Research Fellow) with a proven track-record of high impact research in Super-resolution Microscopy, Single-molecule Spectroscopy, Optical Instrumentation, Advanced Quantitative Fluorescence Microscopy, or related areas.  The successful candidate will lead research projects and supervise junior research staffs and team members on the development and application of novel fluorescence microscopy approaches to study cell biology at the nanoscale level, as a part of a multi-institutional multi-disciplinary research programme on cellular aging.  The project will be housed at the Mechanobiology Institute, National University of Singapore.

The successful candidate must have a Ph.D. degree in Biophysics, Physics, Physical Chemistry, Biomedical Engineering, Optics, or related Bioimaging fields. Prior postdoctoral training experiences and/or career experiences in technically-relevant domains will be strongly favoured.   The candidate is expected to have an outstanding high-impact publication record and proficiency in optical instrumentation, programming (LabVIEW, IDL, MATLAB, for example), data analysis, and visualization. Prior laboratory experiences in cell biology, molecular biology, or electron microscopy are also desirable. Remuneration will be commensurate with qualifications and experiences.

Position: Postdoctoral Fellow 

We are looking for a Postdoctoral Fellow with experiences in Cell Biology, particularly in cell adhesions biology or related mechanobiology fields, to lead a research project on studying adhesion proteins and cytoskeletons using advanced microscopy techniques.  The successful candidate must have a Ph.D. degree in Cell Biology or related fields, with outstanding publication record.    Proficiency in mammalian cell biology, molecular biology, live-cell fluorescence microscopy are desirable.

Compensation is commensurate with experiences and internationally competitive. 

To apply, please send curriculum vitae and 3 references to

Prof. Tony Kanchanawong (biekp -at- nus -dot- edu -dot- sg)

Postdoctoral Fellowship

Candidates are encouraged to apply for the Postdoctoral Fellowship

Lee Kuan Yew Postdoctoral Fellowship

EMBO Fellowship

Human Frontier Science Programme (HFSP) Fellowship

Positions: Ph. D. students

We are looking for highly-motivated and interdisciplinary-minded Ph.D. students.  Students are fully supported by Ph. D. Scholarship (tuition fee and stipend).

Interested students please apply through the following Ph.D. programmes

MBI graduate programme

NUS Graduate School for Integrative Sciences and Engineering (NGS)

Department of Biomedical Engineering, NUS

Scholarship is available for Singapore Citizens and Permanent Residents

Students from ASEAN countries are encouraged to apply for ASEAN Graduate Scholarship

Students from Commonwealth countries are encouraged to apply for Commonwealth Scholarship

International students are also encouraged to apply for graduate scholarship from SINGA

Positions: UROP, Intern, Research Attachment Students

We welcome undergraduate students for Undergraduate Research Opportunity, Internship, or Research Attachment.  Projects are available on CRISPR/Cas9 genome editing, Super-resolution microscopy, Microscope instrumentation.  UROP is available for NUS Engineering students.  Research Attachment is available for Singapore-based students.  International Applicants are welcome to apply for internship.

Please contact Tony at (biekp -at- nus -dot- edu -dot- sg)

Nanoscale Mechano biology
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